Examination of ICER Level in Adipose Tissues of Obesity Patients
Increased adiposity is associated with impairment in glucose uptake in adipocytes, which in part result from the
diminished expression of GLUT4. Parallel to defective glucose metabolism, adipocytes display reduced
production of the insulin-sensitizer adiponectin. An important mechanism responsible for decreased level of
Glut4 and Adipoq in obesity is now advanced.